Vol.100 No.4 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 100 No. 4 April 2007
A Case of Tonsillar Squamous Cell Carcinoma
Arising in a Married Couple
Isao Uemaetomari, Tadamichi Tobita, Keiji Tabuchi,
Hideki Okubo, Tetsuro Wada and Akira Hara
(University Hospital of Tsukuba)
Human papilloma virus (HPV) has previously been reported to be associated with head and neck squamous cell carcinoma (HNSCC), and oral and tonsillar carcinomas highly tend to be associated with HPV. We treated a married couple with tonsillar squamous cell carcinoma, and both husband and wife had same HPV subtype (HPV-16). Although the husband was initially treated by radiotherapy, local recurrence was found in the tonsil nine months after the initial treatment. The recurrent tumor was surgically treated. The wife was treated by radiotherapy, and neither local recurrence nor distant metastasis have been found so far. There have been no reports of a married couple with tonsillar carcinoma of the same HPV type. Thus, we reviewed the practical features of HPV-related tonsillar carcinoma.
Key words : tonsillar carcinoma, married couple, human papilloma virus (HPV)