Vol.100 No.7 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 100 No. 7 Jury 2007
Clinical Analysis of Fine Needle Aspiration Biopsy
for Lymph Nodes of Malignant Lymphoma
Naoki Ashimori and Minako Tsurita
(Numazu City Hospital)
Rieko Yamamoto, Satoru Takebayashi and Hiroyuki Mineta
(Hamamatsu University School of Medicine)
We retrospectively reviewed fine-needle aspiration biopsy diagnosis of malignant lymphoma to evaluate the diagnostic accuracy and pitfalls. Sixty-eight cases of malignant lymphoma and fifty-two cases of non malignant lymphoma evaluated by FNAB were identified between 1997 and 2004. Based on the original diagnosis, 41 (60％) cases had a positive diagnosis of malignant lymphoma, 21 (31％) had a suspicious diagnosis, and 6 (9％) had a false negative diagnosis. On histological examinations DLBCLs yielded a high positive diagnosis, whereas FL and HD had less positive diagnosis and there were also false negative cases. Fourteen (39％) lymphadenitis cases had a suspicious diagnosis and some cases were difficult to differentiate from malignant lymphoma. FNAB is considered a useful and efficient method of estimating malignant lymphoma but we should remain aware of the existence of false negative cases.
Key words : fine needle aspiration biopsy, malignant lymphoma, positive diagnosis, false negative
diagnosis