Vol.100 No.7 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 100 No. 7 Jury 2007
A Case Report of Cicatrical Pemphigoid with Acute Onset
Takeo Nonoda, Keiichi Izuhara, Toshimitsu Ohhashi and Masami Ohnishi
(Oogaki Municipal Hospital)
Nansei Yamada
(Gifu University School of Medicine)
We report a rare case of cicatrical pemphigoid with acute onset. A 54-year-old man had complained of sore throat and swallowing pain six days before he was admitted our hospital. He demonstrated blisters of the oral cavity, lips, gingiva and epiglottis which showed multiple aphta and erosions. As antibiotics (penicillin and cephem) were not effective, we speculated that this was a viral infection or Bechet disease. Since there was no improvement after admittion, we consulted dermatologists regarding the possibility lichen planus, pemphigus or pemphigoid. A diagnosis of cicatrical pemphigoid was established by immunopathological examination of lip biopsy.
Cicatrical pemphigoid is a chronic subepithelial blistering disorders of the mucous membranes. This chronic blistering disorder is characterized by tense bullae on an erythematous base which healed with scarring. The oral mucosa and conjunctiva are common sites of involvement. The esophagus, trachea, nose, and genitalia are sometimes affected. Generally, cicatrical pemphigoid is a chronic progressive disease, but this rare case demonstrated acute onset.
Key words : cicatrical pemphigoid, acute onset, immunopathological, mucous membranes