Vol.100 No.9 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 100 No. 9 September 2007
Efficacy of the Prophylactic Suplatast Tosilate (IPDŽ capsules 100 mg)
for the Treatment of Seasonal Allergies Due to Japanese Cedar and
Cypress Pollen
Shuntaro Inagawa, Meiho Nakayama, Tatsuyuki Banno, Moutatsu Go,
Takako Kamazawa, Naoko Eguchi, Hiroshi Sunagawa, Toru Tanigawa,
Satoshi Iwasaki and Sigeru Inafuku
(Aichi Medical University)
To assess the effects of early intervention with suplatast tosilate
(IPDŽ capsules, 100 mg), a Th2 cytokine inhibitor, in patients with allergies to Japanese cedar and cypress pollen, we studied 93 patients with this type of allergy. Symptom, medication, and symptom medication scores were lower in patients who received early intervention with suplatast tosilate than in those who received suplatast during the pollen season. The results of a survey performed with the Japanese Allergic Rhinitis Standard Quality of Life Questionnaire also indicated that the early intervention group had good outcomes. Early intervention with suplatast was thus an effective treatment for patients with allergies to cedar and Japanese cypress pollen.
We also surveyed the expectations of patients regarding drug treatment. We found that patients want to have drugs that exhibit a prolonged duration of action and are very effective without causing drowsiness.
Key words : prophylactic treatment, Japanese cedar and cypress pollinosis,
IPDŽ