PRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 101 No. 12 December 2008
Hemangiopericytoma of the Head and Neck Region:
Report of Two Cases
Kayoko Higashi-Shingai, Katsumi Mori and Katsuyuki Nakanishi
(Osaka Seamen's Insurance Hospital)
Hidenori Inohara, Yasuhiro Osaki, Keigo Osuga and Takeshi Kubo
(Osaka University)
Yoshiaki Kawasaki
(Kawasaki ENT Clinic)
Kunimitsu Kawahara
(Osaka Prefectural Medical Center for Respiratory and Allergic Diseases)
A hemangiopericytoma is a rare perivascular mesenchymal tumor originating from Zimmerman's pericytes and shows variable malignant potential. Here we report two additional cases of hemangiopericytoma in the head and neck region. One was located in the sinonasal cavity, and the other was in the parapharynx. Endonasal surgery was performed for the sinonasal tumor. Preoperative embolization followed by endoscopic sinus surgery achieved complete excision of the tumor with reduction of intraoperative hemorrhage. There has not been any recurrence for over 65 months to date. The parapharyngeal tumor was excised by retraction of the submandibular gland (cervical approach). There has not been any recurrence for over 96 months to date. Immunohistochemical analysis was helpful for definitive diagnosis of the two tumors. Here in we discuss the diagnosis and treatment of hemangiopericytoma.
Key words :hemangiopericytoma, embolization, endoscopic sinus surgery, immunohistochemistry, vimentin