PRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 95 No. 4 April 2002
Clinical Efficacy of Choto-san with Merislon® and Serenal® on Tinnitus
Keiko Nishioka and Hisako Matsuoka
(Takinomiya General Hospital)
Shigeko Nishioka and Mami Yamamoto
(Okayama University)
Naoto Ichihara and Yumiko Ichihara
(Kagawa Prefectural College of Health Sciences)
Forty-two patients complaining of tinnitus were treated orally with Choto-san (a Chinese medicine), Betahistine Mesilate, and Oxazolam for one month. Overall effectiveness ratings: Twenty-four (57.1%) patients seemed to improve in tone volume, twenty-two (52.4%) in durability, and sixteen (38.1%) in worrying. Even in the early stage of this experiment, twenty-six percent of the subjects seemed to have a greater improvement in tinnitus than those treated with only one of the medicines. It is suggested that these medicines are promising in the treatment of tinnitus because there is a synergic effectiveness in their combination.
Key words : Choto-san, tinnitus, Merislon®, Serenal®, clinical effect