PRACTICA OTO-RHINO-LARYNGOLOGICA

Vol. 95 No. 11  November　2002

A Case of Intrathyroidal Parathyroid Carcinoma

Tomoko Tateya, Kazuhiko Shoji, Shin-ichi Takagita and Yasutaka Kawata
(Tenri Hospital)

Hiroyuki Kitamura
(Takai Hospital)

Yuka Iwahashi
(Shimane Prefectural Central Hospital)

Masakazu Miyazaki
(National Cancer Center Hospital East)

       Intrathyroidal parathyroid carcinoma is very rare. To our knowledge, only 2 cases of intrathyroidal parathyroid carcinoma had been reported in Japan. Recently, we encountered a case of hyperfunctioning intrathyroidal parathyroid carcinoma.
A 16-year-old female had complained of thirst, polyposia and polyuria for 6 months. An elastic hard nodule 2 cm in diameter was palpated on the right thyroid lobe. The serum calcium level was 16.2 mg/dl and serum intact-PTH level was 1100 pg/ml (normal value in serum: 10～60 pg/ml). Based on ultrasonography and ²⁰¹Tl subtraction ^99mTc scanning, primary hyperparathyroidism due to a hyperfunctioning parathyroid gland in the right thyroid lobe was suspected. A right lobectomy and local dissection was performed. The tumor was histologically diagnosed as an intrathyroidal parathyroid carcinoma. The patient was asymptomatic and normocalcemic 29 months after surgery.

Key words : parathyroid carcinoma, intrathyroidal parathyroid, primary hyperparathyroidism

第95巻11号　目次　  Vol.95 No.11 contents