PRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 96 No. 4 April 2003
Two Cases of Laryngopharyngeal Reflux
Disease (LPRD) with Collagen Disease
Takashi Kato and Yoshiharu Sakata
(Suita Municipal Hospital)
Yusuke Watanabe and Takeshi Kubo
(Osaka University Graduate School of Medicine)
Hiroshi Muta
(National Osaka Hospital)
Gastroesophageal reflux disease (GERD) which includes otorhinolaryngologic symptoms is called laryngopharyngeal reflux disease (LPRD). GERD shows a high incidence in progressive systemic sclerosis (PSS) and mixed connective tissue disease (MCTD).
Two cases of LPRD with collagen disease, MCTD and PSS, are reported. The chief complaints were globus sensation and hoarseness. Arytenoid swelling, vocal cord edema and interarytenoid pachydermia were found by laryngeal fiberscopy. The clinical symptoms and findings disappeared after administration of proton pump inhibitor (PPI).
Key words : LPRD, collagen disease, GERD, PSS, MCTD