Vol.99 No.2 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 99 No. 2 February 2006
Maxillary Cancer which Caused Marked
Systemic Inflammatory Reaction
Keigo Honda, Shinzo Tanaka, Masanao Kishimoto,
Yoshihiro Tamura, Hisanobu Tamaki, Ryo Asato and Juichi Ito
(Kyoto University Graduate School of Medicine)
We report a case of maxillary cancer that caused a marked systemic inflammatory reaction including leukocytosis and high blood levels of C-reactive protein. The production of Granulocyte-colony stimulating factor (G-CSF) by tumor cells was demonstrated by immunohistochemical staining. Despite the reported poor prognosis of G-CSF producing tumors, chemoradiotherapy was highly effective and all of the inflammatory indexes settled to within normal limits. The patient is under close follow-up and has been in complete remission for eleven months after the completion of chemoradiotherapy..
Key words :maxillary cancer, G-CSF, chemoradiation therapy