Vol.99 No.4 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 99 No. 4 April 2006
Clinical Analysis of Multiple Primary Cancers in
Patients with Head and Neck Cancer
Satoshi Sonoda, Satoshi Seno, Hironori Sakurai,
Masakazu Hanamitsu and Takeshi Shimizu
(Shiga University Of Medical Science)
Mikio Suzuki
(Ryukyu University)
Hideyuki Kataoka and Hiroya Kitano
(Tottori University)
Recent reports have indicated that the incidence of multiple primary cancers in patients with head and neck cancer has increased. We investigated 25 clinical characteristics of multiple primary cancers in 210 patients who received their initial treatment against their head and neck cancer at our clinic between 1995 and 2002. Clinical stages of these 210 patients were; stage I, 34 cases; stage II, 21; stage III, 29; stage IV, 108; and unknown, 18. Of these 210 patients, 25 patients with hypopharyngeal, laryngeal or mesopharyngeal carcinoma, had multiple primary cancers were diagnosed simultaneously (68％) or metachronously (32％). The multiple primary cancers were frequently observed in the thyroid gland, mesopharynx, larynx, hypopharynx, esophagus and stomach. There were no significant relationships between multiple primary cancers and smoking or drinking habits. It is important to diagnose multiple primary cancers in patients with head and neck cancers as soon as possible.
Key words : multiple primary cancer, head and neck cancer, smoking