PRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 99 No. 5 May 2006
Salivary Duct Carcinoma in the Submandibular
Gland: A Case Report
Hidetaka Shirouzu
(Social Insurance Tagawa Hospital)
Hideki Chijiwa, Keiichi Chijiwa and Tadashi Nakashima
(Kurume University School of Medicine)
Buichiro Takase
(Takase Clinic)
Salivary duct carcinoma is an uncommon tumor and was first described by Kleinsasser et al. in 1968. Its histological features resemble ductal carcinoma of the breast. We experienced a 72-year-old male with salivary duct carcinoma of the submandibular gland with neck metastasis. The tumor was resected with the surrounding tissue and selective neck dissection was performed. Histological examination revealed that the tumor presented with cribriform and papillary patterns of the intraductal growth with comedo necrosis. Postoperative radiation of 50 Gy and chemotherapy (CDDP, THP, CPA) were performed. The patient is alive without any evidence of recurrence at 30 months after surgery.
Key words : salivary duct carcinoma, submandibular gland, comedo necrosis