Vol.99 No.6 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 99 No. 6 June 2006
Selective Intraarterial Infusion Chemotherapy in a Patient
with Maxillary Carcinoma under Artificial Hemodialysis
Takahiro Suzuki, Kiyoto Shiga and Toshimitsu Kobayashi
(Tohoku University Hospital)
When antineoplastic drugs are administered to a patient with impaired or unstable renal function, problems related to the dosage schedule may occur because of differences in pharmacokinetics between patients with normal renal function and those with renal dysfunction. We performed selective intraarterial infusion chemotherapy for a patient with maxillary squamous cell carcinoma who was undergoing hemodialysis for chronic renal failure. Cisplatin at doses of 50 mg/body and docetaxel at doses of 20 mg/body were administered via the maxillary artery twice at a one-week interval. The effect of intraarterial infusion chemotherapy was partial response. We could carry out the subsequential surgery and radiation therapy without severe adverse effects.
Key words : maxillary carcinoma, hemodialysis, cisplatin, docetaxel