Vol.101 No.2 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 101 No. 2 February 2008
A Case of Behcet Disease Improved by Early
Treatment and Diagnosis
Kousuke Yoshifuku and Hiromi Nagano
(Kagoshima Prefectural Oshima Hospital)
Yuichi Kurono
(Kagoshima University)
We report a case of Behcet disease. A 68-year-old female complicated with diabetes mellitus consulted our hospital complaining of intractable oral ulcers that had continued to expand despite treatment with antibiotics and topical steroid at another hospital.
Since she complained of severe oral pain and pain upon swallowing, she received oral cavity care and gargled with azulene sodium sulfate and amphotericin B following admission.
Three days after admission, the patient's complaints decreased. Six days after admission, she complained of oral pain because a vesicle had erupted in the oral cavity. Therefore, we considered herpes stomatitis and treated her with a virucide, but there was no improvement. Since erythema nodosum had erupted on the anterior surface of her leg, the patient was referred to a dermatologist and Behcet disease was suspected even though there were no eye lesions or genital ulcers. Based on the diagnosis, oral steroids and colchicine were administered. Further, hypodermic injection of insulin was administered to control the blood glucose. These treatments were effective and local findings improved day by day. After oral administration of steroids for 2 weeks, she was discharged and there has not been any recurrence to date.
Key words :Behcet disease, intractable oral ulcers, erythema nodosum