PRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 95 No. 6 June 2002
A Case of Laryngeal Papilloma Treated with α-Interferon
Akihiro Sakai
(Tokai University, Yamaguchi University)
Masahiro Takahashi
(Tokai University)
Takuo Ikeda, Hirotaka Hara and Hiroshi Yamashita
(Yamaguchi University)
Masaaki Hiyoshi
(Hiyoshi Clinic)
Although laryngeal papilloma is a benign tumor, it is difficult to control this disease because of the rapid recurrence after surgery. We reported a patient with recurrent laryngeal papilloma who responded well to
α-interferon after laser surgery.
The patient was a 16-year-old man with a history of dyspnea and hoarseness. He underwent laser surgery three times, but the papilloma repeatedly relapsed. We treated him with intramuscular injection of
α-interferon at a dosage of
3×106 IU twice a week for 1 year. Symptoms were rapidly relieved by this therapy. We conclude that
α-interferon may be effective for recurrent laryngeal papilloma after laser surgery.
Key words : laryngeal papilloma, α-interferon, laser surgery