Vol.99 No.3 contentsPRACTICA OTO-RHINO-LARYNGOLOGICA
Vol. 99 No. 3 March 2006
A Case of Paget's Disease of the Temporal Bone,
Having Been Progressed to Total Deafness
Yurika Kimura and Mutsumi Sugiura
(Tokyo Metropolitan Geriatric Hospital)
Nao Makino
(Ome Municipal General Hospital)
Hideji Okuno
(Saginomiya E.N.T. clinic)
Ken Kitamura
(Tokyo Medical and Dental University, Graduate School)
Paget's disease involves disordered bone remodeling by osteoclasts and osteoblasts. Its etiology is unknown and it is a common geriatric disease in England. In Japan, however, it is very rare and only 11 cases with hearing loss due to Paget's disease have been reported. We report a case of Paget's disease that had been initially diagnosed as presbycusis. Hearing in this patient progressed to total deafness 10 years later, and was finally diagnosed as Paget's disease when buccal swelling appeared 20 years after deafness. The patient also complained of bilateral facial spasm. After diagnosis of Paget's disease, third genaration bisphosphanate administration decleased the alkaliphosophatase level to about half. It is important to diagnose hearing loss caused by Paget's disease because early administration of third generation bisphosphanates can prevent the progression of hearing loss and the appearance of other cerebral nerve symptoms.
Key words : Paget's disease, temporal bone, hearing loss, facial spasm